• The added value of multi-state modelling in a randomized controlled trial: The HOVON 102 study re-analyzed 

      Bakunina, Katerina; Putter, Hein; Versluis, Jurjen; Koster, Eva A. S.; van der Holt, Bronno; Manz, Markus G.; Breems, Dimitri A.; Gjertsen, Bjørn Tore; Cloos, Jacqueline; Valk, Peter J. M.; Passweg, Jakob; Pabst, Thomas; Ossenkoppele, Gert J.; Löwenberg, Bob; Cornelissen, Jan J.; de Wreede, Liesbeth C. (Journal article; Peer reviewed, 2022)
      Clofarabine is an active antileukemic drug for subgroups of patients with acute myeloid leukemia (AML). Multi-state models can provide additional insights to supplement the original intention-to-treat analysis of randomized ...
    • Bimodal expression of potential drug target CLL-1 (CLEC12A) on CD34+ blasts of AML patients 

      Ngai, Lok Lam; Ma, Connie Y.; Maguire, Orla; Do, An D.; Robert, Alberto; Logan, Aaron C.; Griffiths, Elizabeth A.; Nemeth, Michael J.; Green, Cherie; Pourmohamad, Tony; van Kuijk, Bo J.; Snel, Alexander N.; Kwidama, Zinia W.; Venniker-Punt, Bianca; Cooper, James; Manz, Markus G.; Gjertsen, Bjørn Tore; Smit, Linda; Ossenkoppele, Gert J.; Janssen, Jeroen J. W. M.; Cloos, Jacqueline; Sumiyoshi, Teiko (Journal article; Peer reviewed, 2021)
      Objectives This study aims to retrospectively assess C-lectin-like molecule 1 (CLL-1) bimodal expression on CD34+ blasts in acute myeloid leukemia (AML) patients (total N = 306) and explore potential CLL-1 bimodal ...